A "Clean Room" is an isolated area with an air conditioning system designed and installed to insure that the quality of the air (temperature, filtration and humidity) is within the limits specified in the project.
Clean rooms are constructed with materials which do not generate residues or dust and are easily cleaned. The correct application of the standards as well as the maintenance of clean rooms is of fundamental importance to obtain the desired quality of the internal air within the standards required by the particular industrial activity.
The first clean rooms appeared in hospitals. About 100 year ago, they discovered that bacteria caused infections. They were then able to substantially reduce infections by using a solution of carbolic acid as an antiseptic solution for sterilizing instruments, hands of the surgeons, and spraying it into the air.
Today clean rooms are used by the following industries:
- Electronic Equipment Manufacture
Manufacture of semiconductor circuits.
- Biotechnology
Manipulation of various "live" products such as viral bacteria, fungus and other animals and plants with the intuition of producing medicines, food products, cosmetics as well as products to aid agriculture and the environment.
- Pharmaceutical Industry
Generally injectable products require a much higher environmental standards than do topical products (those applied on the skin surface) and oral products (products which are taken through the mouth and swallowed). The circulatory system contains lower quantities of bacteria compared to the skin or the stomach, with the exception of the eyes which are more susceptible to infection than skin.
- Surgical Centers
No area in a hospital requires more care in the control of the aseptic environment than the surgical center. The systems which serve the endoscopy and fracture rooms require special projects in order to minimize the concentration of microorganisms in suspension in the air.
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Recommendation of the class of flow in accordance with the application (ml/seg/m˛ of duct) in accordance with NBR 16401-2008